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HomeProduct name listAxitinib Impurity B

Axitinib Impurity B

Axitinib Impurity B Structural

What is Axitinib Impurity B?

The Uses of Axitinib Impurity B

2-(1H-Indazol-6-ylthio)-N-methylbenzamide is a useful intermediate for the preparation of axitinib; an antitumor agent.

Properties of Axitinib Impurity B

Melting point: >148°C (dec.)
Boiling point: 555.7±30.0 °C(Predicted)
Density  1.36±0.1 g/cm3(Predicted)
storage temp.  4°C, Inert atmosphere
solubility  DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form  Solid
pka 13.02±0.40(Predicted)
color  White to Off-White

Safety information for Axitinib Impurity B

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Axitinib Impurity B

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