Apixaban Impurity 102
- CAS NO.:1589504-29-9
- Empirical Formula: C16H17ClN2O2
- Molecular Weight: 304.77
What is Apixaban Impurity 102?
The Uses of Apixaban Impurity 102
3-Chloro-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydropyridin-2(1H)-one is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. 3-Chloro-1-[4-(2-oxopiperidin-1-yl)phenyl]-5,6-dihydropyridin-2(1H)-one is prepared in a multi-step synthesis with the advantages of being low cost, simple, and with large yields and high purity.
Properties of Apixaban Impurity 102
Boiling point: | 545.5±50.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
pka | 1.05±0.20(Predicted) |
Safety information for Apixaban Impurity 102
Computed Descriptors for Apixaban Impurity 102
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin I Tubulysin M (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin B Diethyl Aluminium Cyanide (1.0 M in Toluene) 4-chloro-5-nitropyridin-2-amine 5-bromo-2-chloro-4-methyl-3-nitropyridine 2-cyano-6-chloro-3-nitropyridine 6-bromo-5-methoxypicolinic acid 2,3-Dibromo-5,6-dimethylpyridine 3-bromo-6-chloro-2-methyl-5-nitropyridine 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 3,3,6,6-Tetramethylcyclohexane-1,2-dione 1-(4-Fluorophenyl)piperidin-2-oneRelated products of tetrahydrofuran
Apixaban-13C-D3
Apixaban Impurity 15
3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
Apixaban Impurity 22
2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
Apixaban Impurity 7
Apixaban Impurity 51
1-(4-Methoxyphenyl)-6-(4-iodophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
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