APIGENIN-7-GLUCURONIDE
Synonym(s):4′,5,7-Trihydroxyflavone 7-glucuronide;Apigenin 7-glucuronide;Apigenin 7-O-β-glucuronide;Scutellarin
- CAS NO.：29741-09-1
- Empirical Formula: C21H18O11
- Molecular Weight: 446.36
- MDL number: MFCD23699539
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is APIGENIN-7-GLUCURONIDE?
The Uses of APIGENIN-7-GLUCURONIDE
Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
Definition
ChEBI: Apigenin 7-glucuronide is a member of flavonoids and a glucosiduronic acid.
Properties of APIGENIN-7-GLUCURONIDE
| Melting point: | >300℃ |
| Boiling point: | 841.8±65.0 °C(Predicted) |
| Density | 1.737 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO : 65 mg/mL (145.62 mM; Need ultrasonic) |
| form | powder |
| pka | 2.73±0.70(Predicted) |
| color | Yellowish |
Safety information for APIGENIN-7-GLUCURONIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for APIGENIN-7-GLUCURONIDE
| InChIKey | JBFOLLJCGUCDQP-ZFORQUDYSA-N |
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