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APF

APF Structural

What is APF?

Description

APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively.

What are the applications of Application

APF is a fluorescent reagent used to detect highly reactive oxygen species

Properties of APF

Boiling point: 677.7±55.0 °C(Predicted)
Density  1.52±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF:20.0(Max Conc. mg/mL);47.23(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);23.62(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:3):0.5(Max Conc. mg/mL);1.18(Max Conc. mM)
form  Pale yellow liquid.
pka 9.61±0.20(Predicted)
color  Colorless to light yellow

Safety information for APF

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:IF eye irritation persists: Get medical advice/attention.
P501:Dispose of contents/container to..…

Computed Descriptors for APF

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