APETx2
- CAS NO.：713544-47-9
- Empirical Formula: C196H280N54O61S6
- Molecular Weight: 0
- Update Date: 2023-06-30 15:45:59
What is APETx2?
The Uses of APETx2
APETx2 is a highly pure, synthetic and biologically active peptide toxin.
Biological Activity
APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible acid-sensing ion channel inhibitor of ASIC3 (acid-sensing ion channel) with IC50 of 63 nM. It acts outside the ASIC3 channel. APETx2 reverses acid-induced inflammatory pain.
in vitro
APETx2 (it or im application, 0.022 to 2.2 μM) resulted in a potent and complete reversal of established mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model.
storage
Store at -20°C
Properties of APETx2
| storage temp. | Store at -20°C |
| form | Powder |
| Water Solubility | Soluble to 5 mg/ml in water |
Safety information for APETx2
Computed Descriptors for APETx2
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