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HomeProduct name listAPETx2

APETx2

  • CAS NO.:713544-47-9
  • Empirical Formula: C196H280N54O61S6
  • Molecular Weight: 0
  • Update Date: 2023-06-30 15:45:59

What is APETx2?

The Uses of APETx2

APETx2 is a highly pure, synthetic and biologically active peptide toxin.

Biological Activity

APETx2, a sea anemone peptide from Anthopleura elegantissima, is a selective and reversible acid-sensing ion channel inhibitor of ASIC3 (acid-sensing ion channel) with IC50 of 63 nM. It acts outside the ASIC3 channel. APETx2 reverses acid-induced inflammatory pain.

in vitro

APETx2 (it or im application, 0.022 to 2.2 μM) resulted in a potent and complete reversal of established mechanical hypersensitivity in the complete Freund's adjuvant (CFA) inflammatory pain model.

storage

Store at -20°C

Properties of APETx2

storage temp.  Store at -20°C
form  Powder
Water Solubility  Soluble to 5 mg/ml in water

Safety information for APETx2

Computed Descriptors for APETx2

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