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HomeProduct name listANGIOTENSINOGEN

ANGIOTENSINOGEN

Synonym(s):Angiotensinogen 1-14;Angiotensinogen from hog plasma;Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-leu-Val-Tyr-Ser;Hypertensinogen;Renin substrate

ANGIOTENSINOGEN Structural

What is ANGIOTENSINOGEN?

Purification Methods

This rennin substrate is purified 390-fold from the serum by chromatography on Blue Sepharose, phenyl sepharose, hydroxyapatite and finally by affinity chromatography on 5-hydroxytryptamine (5-HT) sepharose to which it specifically binds to the 5-HT. It is applied to the latter column in 50mM sodium phosphate at pH 7 and after washing, it is eluted by increasing the ionic strength with 100mM sodium phosphate buffer containing 250mM NaCl. The multiple forms are separated by SDSPAGE and have pI 4.40-4.82. [Campbell et al. Biochem J 243 121 1987.]

Properties of ANGIOTENSINOGEN

storage temp.  −20°C
solubility  H2O: 0.3 mg/mL, clear, colorless
form  lyophilized powder

Safety information for ANGIOTENSINOGEN

Computed Descriptors for ANGIOTENSINOGEN

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