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HomeProduct name listANGIOTENSIN III, HUMAN

ANGIOTENSIN III, HUMAN

ANGIOTENSIN III, HUMAN Structural

What is ANGIOTENSIN III, HUMAN?

Description

Angiotensin III (Ang III) is a heptapeptide agonist at the angiotensin 1 (AT1) and AT2 receptors, with a 30-fold higher affinity for AT2 compared with AT1 in HEK293 cells. Ang III is the preferred agonist for renal AT2 receptors, which are responsible for sodium excretion into the urine. Ang III induces the same level of aldosterone synthesis as Ang II but has lower vasoconstrictive activity in vivo. In the brain renin-angiotensin system, Ang III increases sympathetic nerve activity and vasopressin release and dampens the baroreflex leading to higher blood pressure.

Definition

ChEBI: Angiotensin III is a peptide.

Properties of ANGIOTENSIN III, HUMAN

Density  1.39±0.1 g/cm3(Predicted)
storage temp.  −20°C
solubility  H2O: 1.0 mg/mL, clear, colorless
form  Lyophilized.
pka 3.56±0.10(Predicted)
color  White to off-white

Safety information for ANGIOTENSIN III, HUMAN

Computed Descriptors for ANGIOTENSIN III, HUMAN

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