AMINO-THIOPHEN-2-YL-ACETIC ACID

Synonym(s):DL-α-Amino-2-thienylacetic acid;DL-2-(2-Thienyl)glycine

CAS NO.：21124-40-3
Empirical Formula: C6H7NO2S
Molecular Weight: 157.19
MDL number: MFCD00005449
EINECS: 244-225-4
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-30 16:20:48

AMINO-THIOPHEN-2-YL-ACETIC ACID Structural

What is AMINO-THIOPHEN-2-YL-ACETIC ACID?

Purification Methods

Recrystallise 2-(2-thienyl)glycine by dissolving it in H2O (1g in 3 mL), adjusting the pH to 5.5 with aqueous NH3, diluting with MeOH (20 mL), stirring, adjusting the pH to 5.5 and cooling to 0o. Also recrystallise it from small volumes of H2O. [R-isomer: Nishimura et al. Nippon Kagaku Zasshi 82 1688 1961, S-isomer: Johnson & Panetta Chem Abstr 63 14869 1965, Johnson & Hardcastle Chem Abstr 66 10930 1967, RS-isomer: LiBassi et al. Gazz Chim Ital 107 253 1977.] The (±) N-acetyl derivative has m 191o (from H2O) [Schouteenten et al. Bull Soc Chim Fr II 248, II 252 1978].

Properties of AMINO-THIOPHEN-2-YL-ACETIC ACID

Melting point:	208-210 °C(lit.)
Boiling point:	311.8±32.0 °C(Predicted)
Density	1.418
storage temp.	2-8°C
pka	1.88±0.10(Predicted)
BRN	126780
CAS DataBase Reference	21124-40-3(CAS DataBase Reference)

Safety information for AMINO-THIOPHEN-2-YL-ACETIC ACID

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.