Amino-PEG7-acid
- CAS NO.：2376111-92-9
- Empirical Formula: C17H35NO9
- Molecular Weight: 397.47
- MDL number: MFCD26142986
- Update Date: 2024-10-28 23:16:16
What is Amino-PEG7-acid?
Biological Activity
Amino-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Amino-PEG7-acid
| Boiling point: | 514.7±50.0 °C(Predicted) |
| Density | 1.129±0.06 g/cm3(Predicted) |
| pka | 4.28±0.10(Predicted) |
Safety information for Amino-PEG7-acid
Computed Descriptors for Amino-PEG7-acid
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