ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Synonym(s):4,5-Dihydro-3-hydroxy-2(3H)-furanone
- CAS NO.:19444-84-9
- Empirical Formula: C4H6O3
- Molecular Weight: 102.09
- MDL number: MFCD00134268
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-25 17:59:01
What is ALPHA-HYDROXY-GAMMA-BUTYROLACTONE?
Chemical properties
clear colorless to yellow viscous liquid
The Uses of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. 1 It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.
The Uses of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.
What are the applications of Application
α-Hydroxy-γ-butyrolactone is used to initiate the synthesis of series of seco-pseudonucleoside synthons via aminolysis
General Description
α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde.
Purification Methods
It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox
Properties of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Boiling point: | 133 °C/10 mmHg (lit.) |
Density | 1.309 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
form | Viscous Liquid |
pka | 13.07±0.20(Predicted) |
color | Clear colorless to yellow |
BRN | 80587 |
CAS DataBase Reference | 19444-84-9(CAS DataBase Reference) |
Safety information for ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
InChIKey | FWIBCWKHNZBDLS-UHFFFAOYSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
3-Hydroxydihydrofuran-2(3H)-one CAS 19444-84-9View Details
19444-84-9 -
Alpha-hydroxy-gamma-butyrolactone 95% CAS 19444-84-9View Details
19444-84-9 -
α-Hydroxy-γ-butyrolactone CAS 19444-84-9View Details
19444-84-9 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
Lithium ClavulanateView Details
61177-44-4