ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Synonym(s):4,5-Dihydro-3-hydroxy-2(3H)-furanone
- CAS NO.:19444-84-9
- Empirical Formula: C4H6O3
- Molecular Weight: 102.09
- MDL number: MFCD00134268
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-25 17:59:01
What is ALPHA-HYDROXY-GAMMA-BUTYROLACTONE?
Chemical properties
clear colorless to yellow viscous liquid
The Uses of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. 1 It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.
The Uses of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
α-Hydroxy-γ-butyrolactone may be employed as starting reagent in the synthesis of series of seco-pseudonucleoside synthons via aminolysis. It may be employed as starting reagent in the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction.
What are the applications of Application
α-Hydroxy-γ-butyrolactone is used to initiate the synthesis of series of seco-pseudonucleoside synthons via aminolysis
General Description
α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde.
Purification Methods
It has been purified by repeated fractionation and forms a colourless liquid. It has to be distilled at high vacuum; otherwise it will dehydrate. The acetox
Properties of ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Boiling point: | 133 °C/10 mmHg (lit.) |
Density | 1.309 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Sparingly), Methanol (Slightly) |
form | Viscous Liquid |
pka | 13.07±0.20(Predicted) |
color | Clear colorless to yellow |
BRN | 80587 |
CAS DataBase Reference | 19444-84-9(CAS DataBase Reference) |
Safety information for ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
InChIKey | FWIBCWKHNZBDLS-UHFFFAOYSA-N |
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