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HomeProduct name listACRIFLAVINE

ACRIFLAVINE

Synonym(s):3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-diaminoacridine (proflavine);Euflavine;Trypaflavine Neutral

  • CAS NO.:8048-52-0
  • Empirical Formula: C27H25ClN6
  • Molecular Weight: 468.98
  • MDL number: MFCD00064307
  • EINECS: 999-999-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-05 08:26:49
ACRIFLAVINE Structural

What is ACRIFLAVINE?

Chemical properties

Acriflavine hydrochloride is deep orange to brownish-red powder

The Uses of ACRIFLAVINE

Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.

The Uses of ACRIFLAVINE

Fluorescent label for high molecular weight RNA

Safety Profile

Poison by subcutaneous route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. A topical antiseptic used in the treatment of gonorrhea. When heated to decomposition it emits very toxic fumes of NOx and Cl-. See also 3,6-DIAMINO-10 METHYLACRIDINIUM CHLORIDE.

Purification Methods

Treat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.]

Properties of ACRIFLAVINE

Melting point: 179-181 °C
Boiling point: 612.69°C (rough estimate)
Density  1.0933 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  Store at -20°C
solubility  H2O: soluble0.33g/mL (lit.)(lit.)
form  Powder
color  Deep orange to brownish-red
Merck  14,123
CAS DataBase Reference 8048-52-0(CAS DataBase Reference)
EPA Substance Registry System Xanthacridinum (8048-52-0)

Safety information for ACRIFLAVINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for ACRIFLAVINE

Related products of tetrahydrofuran

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