acetyl carbromal
- CAS NO.：77-66-7
- Empirical Formula: C9H15BrN2O3
- Molecular Weight: 279.13
- MDL number: MFCD00045029
- EINECS: 201-047-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is acetyl carbromal?
Originator
Acetylcarbromal ,Pfaltz and Bauer
Definition
ChEBI: Acecarbromal is a N-acylurea.
Manufacturing Process
It was mixed 120 parts of urea and 258 parts of bromodiethylacetylbromide (prepared from diethylacetic acid anhydride and bromine). After 12 hours the mixture was heated for 3 hours at 100°C. The product was mixed with an aqueous solution of sodium bicarbonate and then was filtered. The obtained bromodiethylacetylurea was crystallized from diluted ethanol; melting point 114-118°C. The mixture of 474 parts of bromodiethylacetylurea, 1000 parts of acetic anhydride and 75 parts ZnCl2 was heated at 60°C for 1 hour. The product was stirred with 3000 parts of ice-water and then 1-acetyl-3-(α- bromo-α-ethylbutyryl)urea was filtered; melting point 108-109°C.
Therapeutic Function
Sedative, Hypnotic
Properties of acetyl carbromal
| Melting point: | 108-109° |
| Density | 1.5941 (rough estimate) |
| refractive index | 1.5190 (estimate) |
| EPA Substance Registry System | Butanamide, N-[(acetylamino)carbonyl]-2-bromo-2-ethyl- (77-66-7) |
Safety information for acetyl carbromal
Computed Descriptors for acetyl carbromal
New Products
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