AC-LYS-OH

CAS NO.：1946-82-3
Empirical Formula: C8H16N2O3
Molecular Weight: 188.22
MDL number: MFCD00008233
EINECS: 217-747-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-29 17:45:54

What is AC-LYS-OH?

Chemical properties

Nalpha-Acetyl-L-Lysine is white to almost white crystalline powder

The Uses of AC-LYS-OH

Nalpha-Acetyl-L-Lysine is an antibacterial lysine analogue that targets lysine riboswitches. Nalpha-Acetyl-L-Lysine is used in the metabolomic characterization of ovarian epithelial carcinomas which allows fo r better therapeutic management of patients. The presence of Nalpha-Acetyl-L-Lysine and other N-acetylated amino acids in the urine can be used to detect aminoacylase I deficiency.

The Uses of AC-LYS-OH

Nα-Acetyl-L-lysine is a biologically available N-terminal capped form of the proteinogenic α amino acid L-lysine. Nα-Acetyl-L-lysine is a substrate used to study and characterize lysyl oxidize(s).

Definition

ChEBI: An acetyl-L-lysine where the acetyl group is located at the N2-posiiton.

Synthesis Reference(s)

Canadian Journal of Chemistry, 43, p. 991, 1965 DOI: 10.1139/v65-131

Properties of AC-LYS-OH

Melting point:	256-258 °C (dec.)(lit.)
Boiling point:	323.23°C (rough estimate)
Density	1.1793 (rough estimate)
refractive index	1.4500 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Water (Slightly)
pka	3.57±0.10(Predicted)
form	Powder
color	White
Water Solubility	Soluble in water (miscible), and 80% acetic acid (50 mg/ml--clear colorless solution)).
CAS DataBase Reference	1946-82-3(CAS DataBase Reference)

Safety information for AC-LYS-OH

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.