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HomeProduct name list7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

  • CAS NO.:199327-61-2
  • Empirical Formula: C16H21N3O4
  • Molecular Weight: 319.36
  • MDL number: MFCD12760130
  • EINECS: 429-400-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-12 17:58:41
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one Structural

What is 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one?

Description

7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells.

Chemical properties

White Solid

The Uses of 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Gefitinib intermediate.

Properties of 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Melting point: 233-236 °C
Boiling point: 519.5±60.0 °C(Predicted)
Density  1.32±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 7.10±0.10(Predicted)
color  White to Off-White
CAS DataBase Reference 199327-61-2(CAS DataBase Reference)

Safety information for 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P312:Call a POISON CENTER or doctor/physician if you feel unwell.

Computed Descriptors for 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one

Abamectin manufacturer

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Synergene Active Ingredients Pvt. Ltd.

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