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HomeProduct name list7-Fluoro-4-quinazolone

7-Fluoro-4-quinazolone

7-Fluoro-4-quinazolone Structural

What is 7-Fluoro-4-quinazolone?

The Uses of 7-Fluoro-4-quinazolone

7-Fluoro-4-quinazolone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity.It is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).

The Uses of 7-Fluoro-4-quinazolone

7-Fluoro-4(3H)-quinazolinone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity. 7-Fluoro-4(3H)-quinazolinone is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).

Properties of 7-Fluoro-4-quinazolone

Melting point: 246.0 to 250.0 °C
Boiling point: 293.3±42.0 °C(Predicted)
Density  1.44±0.1 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
form  powder to crystal
pka 0.51±0.20(Predicted)
color  White to Gray to Red
CAS DataBase Reference 16499-57-3(CAS DataBase Reference)

Safety information for 7-Fluoro-4-quinazolone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 7-Fluoro-4-quinazolone

InChIKey KCORZHJVTZIZFD-UHFFFAOYSA-N

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