7-Ethoxy-4-methyl-2H-chromen-2-one
- CAS NO.:87-05-8
- Empirical Formula: C12H12O3
- Molecular Weight: 204.22
- MDL number: MFCD00016971
- EINECS: 201-721-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-26 17:40:34
What is 7-Ethoxy-4-methyl-2H-chromen-2-one?
Chemical properties
White solid; walnut odor. Slightly soluble in alcohol.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
Perfumery, flavoring.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
7-Ethoxy-4-methylcoumarin was an analyte in a study of the structural characterization and retention time simulation of allergenic fragrances.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
7-Ethoxy-4-methylcoumarin may be used in the assay of 4-chlormethyl-7-ethoxycoumarin O-deethylase activity.
What are the applications of Application
7-Ethoxy-4-methylcoumarin is a fluorophore used to monitor functional activity of cytochromes
Definition
ChEBI: 7-Ethoxy-4-methyl-2H-1-benzopyran-2-one is a member of coumarins.
General Description
7-Ethoxy-4-methylcoumarin (EtOMC), also known as ethyl 4-methylumbelliferyl ether, is a coumarin derivative. Its standard molar energy of combustion is ?5888.0 ± 3.2kJ·mol?1 and standard molar enthalpy of formation in the crystalline phase is ?545.4 ± 3.6kJ·mol?1.EtOMC can be prepared by reacting methyl acetoacetate with 3-ethoxyphenol in the presence of boron trifluoride dihydrate.The fluorescence quenching of EtOMC is more effective in the presence 4-hydroxy-TEMPO (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl).
Synthesis
Prod.:
1) from Diketene plus Resorcinol with sulfuric
acid to produce 4-Methyl-7-hydroxy -
coumarin. Ethylation produces subject
material.
2) from Resorcinol plus Ethylacetoacetate,
followed by Ethylation.
Properties of 7-Ethoxy-4-methyl-2H-chromen-2-one
Melting point: | 114-116 °C (lit.) |
Boiling point: | 351.4±37.0 °C(Predicted) |
Density | 1.163±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | DMF: soluble |
form | Solid |
color | White to Off-White |
Odor | at 100.00 %. nutty walnut |
BRN | 169998 |
CAS DataBase Reference | 87-05-8(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Methyl-7-ethoxycoumarin(87-05-8) |
EPA Substance Registry System | 2H-1-Benzopyran-2-one, 7-ethoxy-4-methyl- (87-05-8) |
Safety information for 7-Ethoxy-4-methyl-2H-chromen-2-one
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 7-Ethoxy-4-methyl-2H-chromen-2-one
Abamectin manufacturer
CHROMOSYNTH PVT LTD
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Ivermectin EP Impurity B Rimegepant Impurity 3 Tubulysin I Tubulysin G (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin F Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Calcium Sodium Phosphosilicate IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Benzene butanoic acid, 2-hydroxy-3-iodo-, methyl ester 3-Morpholino-1-[4-(2-oxo-1-piperidyl)phenyl]-5,6-dihydropyridin-2(1H)-one Diethyl 2,5-di(furan-2-yl)terephthalate 3-Morpholino-5,6-dihydropyridin-2(1H)-one Methyl 4-amino-3-(dihexylamino)benzoate 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 6-bromo-4-methyl-2-propyl-1H-1,3-benzodiazole 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine (4R,12aR)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1`,2`;4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acidRelated products of tetrahydrofuran
You may like
-
87-05-8 7- Ethoxy -4- methyl coumarin 98%View Details
87-05-8 -
87-05-8 98%View Details
87-05-8 -
87-05-8 98%View Details
87-05-8 -
7-Ethoxy-4-methylcoumarin CAS 87-05-8View Details
87-05-8 -
7-Ethoxy-4-methyl Coumarin CAS 87-05-8View Details
87-05-8 -
7-ETHOXY-4-METHYLCOUMARIN CAS 87-05-8View Details
87-05-8 -
6390-09-6View Details
6390-09-6 -
6-Bromo indoleView Details