7-Ethoxy-4-methyl-2H-chromen-2-one
- CAS NO.:87-05-8
- Empirical Formula: C12H12O3
- Molecular Weight: 204.22
- MDL number: MFCD00016971
- EINECS: 201-721-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 08:26:49
What is 7-Ethoxy-4-methyl-2H-chromen-2-one?
Chemical properties
White solid; walnut odor. Slightly soluble in alcohol.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
Perfumery, flavoring.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
7-Ethoxy-4-methylcoumarin was an analyte in a study of the structural characterization and retention time simulation of allergenic fragrances.
The Uses of 7-Ethoxy-4-methyl-2H-chromen-2-one
7-Ethoxy-4-methylcoumarin may be used in the assay of 4-chlormethyl-7-ethoxycoumarin O-deethylase activity.
What are the applications of Application
7-Ethoxy-4-methylcoumarin is a fluorophore used to monitor functional activity of cytochromes
Definition
ChEBI: 7-Ethoxy-4-methyl-2H-1-benzopyran-2-one is a member of coumarins.
General Description
7-Ethoxy-4-methylcoumarin (EtOMC), also known as ethyl 4-methylumbelliferyl ether, is a coumarin derivative. Its standard molar energy of combustion is ?5888.0 ± 3.2kJ·mol?1 and standard molar enthalpy of formation in the crystalline phase is ?545.4 ± 3.6kJ·mol?1.EtOMC can be prepared by reacting methyl acetoacetate with 3-ethoxyphenol in the presence of boron trifluoride dihydrate.The fluorescence quenching of EtOMC is more effective in the presence 4-hydroxy-TEMPO (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl).
Synthesis
Prod.:
1) from Diketene plus Resorcinol with sulfuric
acid to produce 4-Methyl-7-hydroxy -
coumarin. Ethylation produces subject
material.
2) from Resorcinol plus Ethylacetoacetate,
followed by Ethylation.
Properties of 7-Ethoxy-4-methyl-2H-chromen-2-one
Melting point: | 114-116 °C (lit.) |
Boiling point: | 351.4±37.0 °C(Predicted) |
Density | 1.163±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | DMF: soluble |
form | Solid |
color | White to Off-White |
Odor | at 100.00 %. nutty walnut |
BRN | 169998 |
CAS DataBase Reference | 87-05-8(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Methyl-7-ethoxycoumarin(87-05-8) |
EPA Substance Registry System | 2H-1-Benzopyran-2-one, 7-ethoxy-4-methyl- (87-05-8) |
Safety information for 7-Ethoxy-4-methyl-2H-chromen-2-one
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 7-Ethoxy-4-methyl-2H-chromen-2-one
Abamectin manufacturer
CHROMOSYNTH PVT LTD
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