7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
- CAS NO.：230615-70-0
- Empirical Formula: C15H12F3N3O
- Molecular Weight: 307.27
- MDL number: MFCD23701601
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-10 11:57:46
![7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline) Structural](https://img.chemicalbook.in/CAS/GIF/230615-70-0.gif)
What is 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)?
Description
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(trifluoroacetyl)varenicline) is an important pharmaceutical intermediate compound which is used in the preparation of varenicline. Varenicline is an oral smoking cessation aid drug. It works by blocking the pleasant effects of nicotine (from smoking) on the brain.
The Uses of 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.
Properties of 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
| Melting point: | 164-166 ºC |
| Boiling point: | 491.9±45.0 °C(Predicted) |
| Density | 1.449 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 1.50±0.20(Predicted) |
| color | White to Off-White |
Safety information for 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(Trifluoroacetyl)varenicline)
Abamectin manufacturer
Radison Labs Private Limited
1Y
Phone:+91-7337551966
Whatsapp: +91-7337551966
product: 2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%
Riddhesh Pharmachem
1Y
Phone:+91-9106014993
Whatsapp: +91 9324548771
product: 230615-70-0 2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 98%
Apiqule Pharmachem LLP
1Y
Phone:+91-9904897541
Whatsapp: +91-9904897541
product: 2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![5,9-Methanoimidazo[4,5-h][3]benzazepine,1,5,6,7,8,9-hexahydro-(9CI)](https://img.chemicalbook.in/CAS/20210111/GIF/357424-12-5.gif)
You may like
-
![230615-70-0 2,2,2-trifluoro-1- (6,7,9,10-tetrahydro-8H-6, 10methanoazepino [4,5-g] quinoxalin-8-yl) ethan-1-one 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/2267ea17-64ed-4a78-ba61-b30601925487.png)
230615-70-0 2,2,2-trifluoro-1- (6,7,9,10-tetrahydro-8H-6, 10methanoazepino [4,5-g] quinoxalin-8-yl) ethan-1-one 98%View Details
230615-70-0 -
230615-70-0 98%View Details
230615-70-0 -
![2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/7d684c18-3b66-41bd-baf2-f7bedbb5581a.png)
2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%View Details
230615-70-0 -
![230615-70-0 2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 98%](https://img.chemicalbook.in//ProductImageIndia/2024-03/Raw/757a3c03-61f9-4e84-8f40-ee9d444bcd11.png)
230615-70-0 2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 98%View Details
230615-70-0 -
230615-70-0 98%View Details
230615-70-0 -
![2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%](https://img.chemicalbook.in//Content/image/CP5.jpg)
2,2,2-Trifluoro-1-(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaen-14-yl)ethanone 230615-70-0 99%View Details
230615-70-0 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.