6-METHYLPYRAZINE-2-CARBOXYLIC ACID
- CAS NO.：5521-61-9
- Empirical Formula: C6H6N2O2
- Molecular Weight: 138.12
- MDL number: MFCD08705756
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:07
What is 6-METHYLPYRAZINE-2-CARBOXYLIC ACID?
The Uses of 6-METHYLPYRAZINE-2-CARBOXYLIC ACID
6-METHYLPYRAZINE-2-CARBOXYLIC ACID can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
The Uses of 6-METHYLPYRAZINE-2-CARBOXYLIC ACID
6-Methylpyrazinecarboxylic Acid can be used to synthesize compounds that are active against M.tuberculosis H37Rv. Similarly, it can be used to synthesize compounds that are useful for the inhibition, prevention or therapy of tumor cell invasion, metastasis, inflammation, hepatitis, or liver dysfunction.
Synthesis
2,6-Dimethylpyrazine (500mg, 4.60mmol) was dissolved in water (10ml), heated at 700C and KMnO4 in water (25ml) was added dropwise. The mixture was stirred and heated overnight. After cooling to room temperature the MnO2 cake was filtered and washed with water several times. The filtrate was acidified with 5M HCI solution (pH 1.5) and extracted with ethyl acetate (3 x 50ml). The residue was dried over magnesium sulphate, filtered and evaporated to afford the product (D25); MS (ES+) m/e 139 [M+H]+.
Properties of 6-METHYLPYRAZINE-2-CARBOXYLIC ACID
| Melting point: | 138-140℃ |
| Boiling point: | 302.8±37.0 °C(Predicted) |
| Density | 1.319 |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.10±0.10(Predicted) |
| color | White to off-white |
Safety information for 6-METHYLPYRAZINE-2-CARBOXYLIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-METHYLPYRAZINE-2-CARBOXYLIC ACID
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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