6-METHYLMERCAPTOPURINE RIBOSIDE
Synonym(s):6-(Methylthio)-9-β-D -ribofuranosyl-9H-purine;6MMPr
- CAS NO.：342-69-8
- Empirical Formula: C11H14N4O4S
- Molecular Weight: 298.32
- MDL number: MFCD00022826
- EINECS: 206-442-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 6-METHYLMERCAPTOPURINE RIBOSIDE?
Chemical properties
white powder
The Uses of 6-METHYLMERCAPTOPURINE RIBOSIDE
6-Methylmercaptopurine Riboside (cas# 342-69-8) is a compound useful in organic synthesis.
The Uses of 6-METHYLMERCAPTOPURINE RIBOSIDE
6-Methylmercaptopurine riboside (6MMPr) is used in studies on thiopurine metabolism by enzymes such as inosine-5′-monophosphate dehydrogenase and thiopurine methyltransferase. 6MMPr may also be used to study mechanisms of bovine viral diarrhea virus (BVDV) inhibition.
What are the applications of Application
6-Methylmercaptopurine riboside is a chemical used to study thiopurine metabolism by enzymes
Definition
ChEBI: A thiopurine that is inosine in which the aromatic hydroxy group is replaced by a methylsulfanediyl group.
General Description
White powder.
Air & Water Reactions
Slightly soluble in water.
Biochem/physiol Actions
6-Methylmercaptopurine riboside (6MMPR) is a modified thiopurine nucleoside involved in the inhibition of purine synthesis. It exhibits anti-viral effects against various viruses. 6MMPR is an analog of purine and an inhibitor of nerve growth factor-activated protein kinase N.
Safety Profile
Poison by intraperitoneal route. Experimental teratogenic effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO, and NOx.
Properties of 6-METHYLMERCAPTOPURINE RIBOSIDE
| Melting point: | 166°C |
| Density | 1.4113 (rough estimate) |
| refractive index | 1.6270 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability: | Incompatible with strong oxidizing agents. |
| EPA Substance Registry System | 6-Methylmercaptopurine riboside (342-69-8) |
Safety information for 6-METHYLMERCAPTOPURINE RIBOSIDE
Computed Descriptors for 6-METHYLMERCAPTOPURINE RIBOSIDE
New Products
2,2-diethoxyethanethioamide Tubulysin H Tubulysin I 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 3-METHYLAZETIDIN-3-OL HYDROCHLORIDE 4-(Benzyloxy)-3-bromophenylacetic Acid 4,4-DIFLUOROCYCLOHEXANAMINE 2,2-Difluoropropanol CYCLOBUTYLAMINE HYDROCHLORIDE 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(2-Formylphenoxy) acetic acid 1-Aminoindan Hydrochloride Magnesium Trisilicate Lubiprostone Latanoprostene Bunod Flame Retardant Zinc Borate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
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