6-Methoxy-2-naphthaldehyde

Chemical properties

yellow to beige-yellow crystals or crystalline

The Uses of 6-Methoxy-2-naphthaldehyde

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluoresce nt substrates for inhibition studies relating to hypertension and vascular inflammation.

The Uses of 6-Methoxy-2-naphthaldehyde

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluorescent substrates for inhibition studies relating to hypertension and vascular inflammation. It is also used as intermediate of Nabumetone.

The Uses of 6-Methoxy-2-naphthaldehyde

6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:

• 4-(6-methoxy-2-naphthyl)but-3-en-2-one
• 4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one
• 5-(6-methoxy-2-naphthyl)pentan-3-one

It may also be used in the synthesis of the following chalcone derivatives:

• (2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
• (2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
• (2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one
• (2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

What are the applications of Application

6-Methoxy-2-naphthaldehyde is a diagnostic reagent in tumor studies

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4587, 1988 DOI: 10.1021/jo00254a035

General Description

6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.

Flammability and Explosibility

Not classified