6-Hydroxy-1-tetralone
Synonym(s):6-Hydroxy-1-tetralone
- CAS NO.:3470-50-6
- Empirical Formula: C10H10O2
- Molecular Weight: 162.19
- MDL number: MFCD00156670
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is 6-Hydroxy-1-tetralone?
Chemical properties
gray powder
The Uses of 6-Hydroxy-1-tetralone
6-Hydroxy-1-tetralone is used as a starting material for a one-pot conversion of phenols to anilines.
The Uses of 6-Hydroxy-1-tetralone
6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone (6-Hydroxy-1-tetralone) may be used in the synthesis of:
- 5-chloromethyl-6-hydroxy-3,4-dihydro-1(2H)-naphthalenone
- 6-(4-(3-(piperidin-1-yl)propoxy)benzyloxy)-1-tetralone
- 6-(3-(piperidin-1-yl)propoxy)-1-tetralone
Synthesis Reference(s)
Journal of Medicinal Chemistry, 41, p. 1068, 1998 DOI: 10.1021/jm970527v
Journal of the American Chemical Society, 99, p. 5810, 1977 DOI: 10.1021/ja00459a052
General Description
6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone (6-Hydroxy-1-tetralone) can be prepared by the demethylation of 6-methoxy-3,4-dihydro-1(2H)-naphthalenone. It participates in the synthesis of 2-alkylamino-6-hydroxy-5-hydroxymethyl-1,2,3,4-tetrahydro-1-naphthalenols. Its pKa value has been reported to be 7.74.
Properties of 6-Hydroxy-1-tetralone
Melting point: | 154-157 °C(lit.) |
Boiling point: | 358.0±31.0 °C(Predicted) |
Density | 1.236±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,Room Temperature |
form | Crystalline Powder |
pka | 8.22±0.20(Predicted) |
color | Off-white to brown |
CAS DataBase Reference | 3470-50-6(CAS DataBase Reference) |
Safety information for 6-Hydroxy-1-tetralone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 6-Hydroxy-1-tetralone
InChIKey | FNSQPQKPPGALFA-UHFFFAOYSA-N |
Abamectin manufacturer
Prolife Bio Chemical Industries Pvt Ltd
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product: 6-Hydroxy-1-Tetralone 99%
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