6-Demethoxylnobiletin
- CAS NO.：17290-70-9
- Empirical Formula: C20H20O7
- Molecular Weight: 372.37
- MDL number: MFCD21333406
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is 6-Demethoxylnobiletin?
Chemical properties
Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from orange peel.
Definition
ChEBI: Isosinensetin is an ether and a member of flavonoids.
Biological Activity
6-Demethoxylnobiletin, a methoxyflavonoid extracted from green peel, has inhibitory effect on p-glycoprotein (P-gp) in MDR1-MDCKII cells.
Properties of 6-Demethoxylnobiletin
| Melting point: | 198-199℃ |
| Boiling point: | 565.3±50.0 °C(Predicted) |
| Density | 1.244±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble |
| form | A solid |
| color | Off-white to light yellow |
Safety information for 6-Demethoxylnobiletin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for 6-Demethoxylnobiletin
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