6-CARBOXYFLUORESCEIN DIACETATE
- CAS NO.：3348-03-6
- Empirical Formula: C25H16O9
- Molecular Weight: 460.39
- MDL number: MFCD00036871
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 13:17:44
What is 6-CARBOXYFLUORESCEIN DIACETATE?
The Uses of 6-CARBOXYFLUORESCEIN DIACETATE
6-CARBOXYFLUORESCEIN DIACETATE is used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin
The Uses of 6-CARBOXYFLUORESCEIN DIACETATE
6-Carboxyfluorescein Diacetate is a fluorescent polyanionic probe used to detect changes intracellular pH. In addition, 6-Carboxyfluorescein Diacetate derivatives can be used as staining agents for flow cytometry to visualize cells undergoing apoptosis or necrosis.
Properties of 6-CARBOXYFLUORESCEIN DIACETATE
| Melting point: | 152–153°C |
| Boiling point: | 701.6±60.0 °C(Predicted) |
| Density | 1.57±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | Solid |
| pka | 6.4(at 25℃) |
| color | Light yellow or off-white solid |
| PH Range | Weak green ' uorescence (6.0) to strong green ' uourescence (7.2) |
| λmax | <300nm |
| Major Application | Fluorescent probes, detecting cells, microorganisms, yeasts, antifungal agent, antibacterials agent |
| Biological Applications | Analyzing/detecting
cells;counting/
detecting/evaluating microorganisms;detecting/
measuring bacteria;quantifying adhesion of
tumor cells to endothelial monolayers;
measuring
gas (carbon dioxide or ammonia) concentration
in body luids;
monitoring intracellular nitric
oxide production;screening xenobiotic phloem
mobility in plants;
, studying low-density
lipoprotein (LDL)/cholesterol metabolism;apoptosis
assay;method for antifungal susceptibility
testing;
, as a substrate for measuring esterase
activity |
| CAS DataBase Reference | 3348-03-6(CAS DataBase Reference) |
Safety information for 6-CARBOXYFLUORESCEIN DIACETATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 6-CARBOXYFLUORESCEIN DIACETATE
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