6-Bromoimidazo[1,2-a]pyridine
- CAS NO.：6188-23-4
- Empirical Formula: C7H5BrN2
- Molecular Weight: 197.03
- MDL number: MFCD06496200
- EINECS: 689-291-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-25 16:21:11
![6-Bromoimidazo[1,2-a]pyridine Structural](https://img.chemicalbook.in/CAS/GIF/6188-23-4.gif)
What is 6-Bromoimidazo[1,2-a]pyridine?
Chemical properties
White crystalline powder
The Uses of 6-Bromoimidazo[1,2-a]pyridine
It is used in organic syntheses and as pharmaceutical intermediates. The best results were obtained with lactams that could be introduced on the 6-bromoimidazo[1,2-a]pyridine. 1,2-dihydro-5-imidazo [1,2-a]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride monohydrate 6 was synthesized in 5 steps from 6-bromoimidazo[1,2-a] pyridine using [2- 14 C] cyanoacetamide as the source of the radiolabel.
Synthesis
The method for synthesizing the 6-bromoimidazo [1,2-a] pyridine comprises the following steps that 2-amidogen-5 bromine-pyridine reacts with a 40% chloroacetaldehyde aqueous solution at the temperature between 25 DEG C and 50 DEG C and after 2 to 24 hours, the 6-bromoimidazo [1,2-a] pyridine is obtained.
Properties of 6-Bromoimidazo[1,2-a]pyridine
| Melting point: | 76-78 °C |
| Boiling point: | 165 °C(Press: 1.5 Torr) |
| Density | 1.69±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 5.10±0.50(Predicted) |
| color | Faint beige |
| Water Solubility | slightly soluble in water. |
| CAS DataBase Reference | 6188-23-4(CAS DataBase Reference) |
Safety information for 6-Bromoimidazo[1,2-a]pyridine
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 6-Bromoimidazo[1,2-a]pyridine
| InChIKey | FXPMFQUOGYGTAM-UHFFFAOYSA-N |
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product: 6-Bromoimidazo[1,2-a]pyridine 98%
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