6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

CAS NO.：1231930-33-8
Empirical Formula: C11H12BrFN2
Molecular Weight: 271.13
MDL number: MFCD16660227
EINECS: 807-019-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-03 15:02:24

What is 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole?

The Uses of 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.

Flammability and Explosibility

Not classified

Properties of 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Boiling point:	353.4±22.0 °C(Predicted)
Density	1.49
storage temp.	Sealed in dry,Room Temperature
pka	3.48±0.10(Predicted)
InChI	InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3

Safety information for 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Computed Descriptors for 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

InChIKey	SJQZRZLUEGCXFN-UHFFFAOYSA-N
SMILES	C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1

New Products

4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acid

Related products of tetrahydrofuran

1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-

4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde

5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine

PF-01367338

2-bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one

1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

Hexafluoroisopropyl methyl ether

GALDEN (TM) HT70