6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

CAS NO.：1231930-33-8
Empirical Formula: C11H12BrFN2
Molecular Weight: 271.13
MDL number: MFCD16660227
EINECS: 807-019-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-04-03 15:02:24

What is 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole?

The Uses of 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.

Flammability and Explosibility

Not classified

Properties of 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Boiling point:	353.4±22.0 °C(Predicted)
Density	1.49
storage temp.	Sealed in dry,Room Temperature
pka	3.48±0.10(Predicted)
InChI	InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3

Safety information for 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Computed Descriptors for 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

InChIKey	SJQZRZLUEGCXFN-UHFFFAOYSA-N
SMILES	C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1

New Products

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GALDEN (TM) HT70