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HomeProduct name list6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromo-1,3-dihydro-2H-indol-2-one

  • CAS NO.:99365-40-9
  • Empirical Formula: C8H6BrNO
  • Molecular Weight: 212.04
  • MDL number: MFCD02179605
  • EINECS: 800-899-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
6-Bromo-1,3-dihydro-2H-indol-2-one Structural

What is 6-Bromo-1,3-dihydro-2H-indol-2-one?

Chemical properties

Light yelllow crystal

The Uses of 6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromo-2-Oxindole is an indolinone derivative used for the preparation of p38α inhibitors as potential antiinflammatories.

The Uses of 6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromooxindole derivative is used in the preparation of p38alpha inhibitors as potential anti- inflammatories. It is used as an intermediate in pharmaceuticals.

Properties of 6-Bromo-1,3-dihydro-2H-indol-2-one

Melting point: 217-221 °C(lit.)
Boiling point: 343.6±42.0 °C(Predicted)
Density  1.666±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSo
form  Solid
pka 13.39±0.20(Predicted)
color  Orange
Water Solubility  Slightly soluble in water.
CAS DataBase Reference 99365-40-9(CAS DataBase Reference)

Safety information for 6-Bromo-1,3-dihydro-2H-indol-2-one

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H301:Acute toxicity,oral
H312:Acute toxicity,dermal
H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H341:Germ cell mutagenicity
H361:Reproductive toxicity
H371:Specific target organ toxicity, single exposure
H372:Specific target organ toxicity, repeated exposure
H373:Specific target organ toxicity, repeated exposure
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P272:Contaminated work clothing should not be allowed out of the workplace.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.
P405:Store locked up.

Computed Descriptors for 6-Bromo-1,3-dihydro-2H-indol-2-one

InChIKey JARRYVQFBQVOBE-UHFFFAOYSA-N

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