5(S)-HPEPE

CAS NO.：143292-98-2
Empirical Formula: C20H30O4
Molecular Weight: 334.45
MDL number: MFCD00065834
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

What is 5(S)-HPEPE?

Description

5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA.¹ It is metabolized to LTA₅, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

What are the applications of Application

5(S)-HpEPE is a peroxidase substrate

Definition

ChEBI: 5S-HpEPE is a HPETE.

References

1. Kulkarni, P.S., Kaufman, P.L., and Srinivasan, B.D. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid J. Ocul. Pharmacol. 3(4),349-356(1987).

Properties of 5(S)-HPEPE

storage temp.	Store at -20°C
solubility	0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Safety information for 5(S)-HPEPE

Computed Descriptors for 5(S)-HPEPE

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