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HomeProduct name list5(S), 15(S)-DIHETE

5(S), 15(S)-DIHETE

5(S), 15(S)-DIHETE Structural

What is 5(S), 15(S)-DIHETE?

Description

5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.

The Uses of 5(S), 15(S)-DIHETE

5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE. It potentiates the degranulation of human PMNL in response to PAF, but not fMLP, calcium ionophore A23187, or LTB4. 5(S),15(S)-DiHETE is chemotactic for eosinophils with an ED50 value of 0.3 μM.

The Uses of 5(S), 15(S)-DIHETE

5(S),15(S)-DiHETE is an enhancer of neutrophil degranulation and potent chemotaxin.

What are the applications of Application

5(S),15(S)-DiHETE is an enhancer of neutrophil degranulation and potent chemotaxin

Definition

ChEBI: 5(S),15(S)-DiHETE is a DiHETE that is (6E,8Z,11Z,13E)-icosatetraenoic acid in which the two hydroxy substituents are placed at the 5S- and 15S-positions. It has a role as a rat metabolite and a human xenobiotic metabolite. It is a conjugate acid of a 5(S),15(S)-DiHETE(1-).

Properties of 5(S), 15(S)-DIHETE

storage temp.  -20°C
solubility  DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
form  Colorless liquid.
color  Colorless to light yellow

Safety information for 5(S), 15(S)-DIHETE

Computed Descriptors for 5(S), 15(S)-DIHETE

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