5,6,7,8-Tetrahydroquinoxaline

Synonym(s):Cyclohexapyrazine;Nutty quinoxaline;Tetrahydroquinoxaline

CAS NO.：34413-35-9
Empirical Formula: C8H10N2
Molecular Weight: 134.18
MDL number: MFCD00038078
EINECS: 252-002-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-24 19:19:26

5,6,7,8-Tetrahydroquinoxaline Structural

What is 5,6,7,8-Tetrahydroquinoxaline?

Chemical properties

CLEAR VERY SLIGHTLY YELLOW LIQUID

Occurrence

Reported found in cocoa, coffee, wheat bread, fried cured pork, pork liver, cocoa, coffee, roasted filbert, roasted peanut and roasted sesame seeds.

Preparation

By condensation of alicyclic α, β-diketone with an α, β-diamine; condensation of an acyclic α, β-diamine with an α, β-dicarbonyl.

Definition

ChEBI: 5,6,7,8-Tetrahydroquinoxaline is a member of pyrazines.

Aroma threshold values

Aroma characteristics at 1.0%: nutty roasted corn chip, peanut, hazelnut, toasted coconut, coffee, graham cracker, popcorn, toasted and roasted grain.

Taste threshold values

Taste characteristics from 5 to 10 ppm: roasted nutty, corn and popcorn, toasted grain and corn chip, taco fatty, basmati rice, hazelnut and roasted coffee-like. Taste characteristics at 10 ppm: nutty, musty, corn taco and popcorn-like.

Properties of 5,6,7,8-Tetrahydroquinoxaline

Boiling point:	85 °C3 mm Hg(lit.)
Density	1.061 g/mL at 25 °C(lit.)
refractive index	n20/D 1.542(lit.)
FEMA	3321 \| 5,6,7,8-TETRAHYDROQUINOXALINE
Flash point:	195 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	2.24±0.20(Predicted)
Specific Gravity	1.1334
color	Colorless to Yellow to Green
Odor	at 0.10 % in dipropylene glycol. musty nut roasted bean cereal corn chip cheese
Water Solubility	slightly soluble
JECFA Number	952
BRN	957053
CAS DataBase Reference	34413-35-9(CAS DataBase Reference)
NIST Chemistry Reference	5,6,7,8-Tetrahydroquinoxaline(34413-35-9)
EPA Substance Registry System	Quinoxaline, 5,6,7,8-tetrahydro- (34413-35-9)

Safety information for 5,6,7,8-Tetrahydroquinoxaline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.