5,6,7,8-TETRAHYDROISOQUINOLINE

CAS NO.：36556-06-6
Empirical Formula: C9H11N
Molecular Weight: 133.19
MDL number: MFCD00012168
EINECS: 253-098-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:37

What is 5,6,7,8-TETRAHYDROISOQUINOLINE?

The Uses of 5,6,7,8-TETRAHYDROISOQUINOLINE

5,6,7,8-Tetrahydroisoquinoline was used in total synthesis of (±)-desoxycodeine-D. It was also used in the synthesis of 7,8-dihydroisoquinolin-5(6H)-one.

Synthesis Reference(s)

Tetrahedron, 39, p. 2869, 1983 DOI: 10.1016/S0040-4020(01)92154-4

General Description

Reduction of 5,6,7,8-tetrahydroisoquinoline with sodium in ethanol gives trans-decahydroquinolines. 5,6,7,8-Tetrahydroisoquinoline is also referred as Bz-tetrahydroisoquinoline.

Properties of 5,6,7,8-TETRAHYDROISOQUINOLINE

Melting point:	146.5°C
Boiling point:	106-108 °C13 mm Hg(lit.)
Density	1.03 g/mL at 25 °C(lit.)
refractive index	n20/D 1.545(lit.)
Flash point:	212 °F
storage temp.	Inert atmosphere,Room Temperature
form	Liquid
pka	6.37±0.20(Predicted)
color	Clear pale yellow
CAS DataBase Reference	36556-06-6(CAS DataBase Reference)

Safety information for 5,6,7,8-TETRAHYDROISOQUINOLINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.