5-TRANS U-44069

CAS NO.：330796-57-1
Empirical Formula: C21H34O4
Molecular Weight: 350.49
MDL number: MFCD00077407
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 09:02:17

What is 5-TRANS U-44069?

Description

5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 . It inhibits microsomal prostaglandin E₂ synthase (mPGES) when used at a concentration of 10 μM.¹

References

1. Quraishi, O., Mancini, J.A., and Riendeau, D. Inhibition of inducible prostaglandin E₂ synthase by 15-deoxy-Δ^12,14-prostaglandin J₂ and polyunsaturated fatty acids Biochem. Pharmacol. 63(6),1183-1189(2002).

Properties of 5-TRANS U-44069

Boiling point:	519.7±35.0 °C(Predicted)
Density	1.092±0.06 g/cm3(Predicted)
solubility	DMF: >100 mg/ml (from U-46619); DMSO: >100 mg/ml (from U-46619); Ethanol: >100 mg/ml (from U-46619); PBS pH 7.2: >2 mg/ml (from U-46619)
pka	4.76±0.10(Predicted)

Safety information for 5-TRANS U-44069

Computed Descriptors for 5-TRANS U-44069

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