5-(piperazin-1-yl)pyridin-2-aMine
- CAS NO.：1082876-26-3
- Empirical Formula: C9H14N4
- Molecular Weight: 178.23
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-12 20:24:49
What is 5-(piperazin-1-yl)pyridin-2-aMine?
The Uses of 5-(piperazin-1-yl)pyridin-2-aMine
5-?(1-?Piperazinyl)?-?2-?pyridinamine is a reagent used in the synthesis of anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
Properties of 5-(piperazin-1-yl)pyridin-2-aMine
| Boiling point: | 401.7±40.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.67±0.10(Predicted) |
| color | Pale Brown to Light Brown |
Safety information for 5-(piperazin-1-yl)pyridin-2-aMine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-(piperazin-1-yl)pyridin-2-aMine
Abamectin manufacturer
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product: 1082876-26-3 Palbociclib EP Impurity-A 98%
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