5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
- CAS NO.:1363380-51-1
- Empirical Formula: C6H3ClN4O2
- Molecular Weight: 198.57
- MDL number: MFCD22415211
- EINECS: 251-228-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-16 11:59:48
What is 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine?
The Uses of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.
Properties of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
Melting point: | 163 - 165°C |
Density | 1.85±0.1 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Chloroform (Slightly, Heated), DMSO (Slightly) |
form | Solid |
pka | -3.59±0.40(Predicted) |
color | Purple |
Safety information for 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine manufacturer
CiVentiChem Private Limited
1Y
Phone:+91-8897000471
Whatsapp: +91 8897000471
product: 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 98%
ARRKEM LIFE SCIENCES PRIVATE LIMITED
1Y
Phone:+91-8148739767
Whatsapp: +91-8148739767
product: 1363380-51-1 98%
Mekong pharmaceuticals pvt ltd
1Y
Phone:+918008212221
Whatsapp: +91- 8008212221
product: 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 1363380-51-1 98%
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