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HomeProduct name list5-CHLORO-2-NITROANISOLE

5-CHLORO-2-NITROANISOLE

  • CAS NO.:6627-53-8
  • Empirical Formula: C7H6ClNO3
  • Molecular Weight: 187.58
  • MDL number: MFCD00007288
  • EINECS: 229-594-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:32
5-CHLORO-2-NITROANISOLE Structural

What is 5-CHLORO-2-NITROANISOLE?

Chemical properties

SLIGHTLY YELLOW TO GREEN CRYSTALLINE POWDER

The Uses of 5-CHLORO-2-NITROANISOLE

5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells.

The Uses of 5-CHLORO-2-NITROANISOLE

5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs (1). In addition, it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells (2).

Properties of 5-CHLORO-2-NITROANISOLE

Melting point: 70-72 °C(lit.)
Boiling point: 289.1±20.0 °C(Predicted)
Density  1.4219 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform, Ethyl Acetate
form  Solid
color  Yellow
CAS DataBase Reference 6627-53-8(CAS DataBase Reference)
EPA Substance Registry System 5-Chloro-2-nitroanisole (6627-53-8)

Safety information for 5-CHLORO-2-NITROANISOLE

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for 5-CHLORO-2-NITROANISOLE

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