5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
- CAS NO.：174672-06-1
- Empirical Formula: C7H6BClO2
- Molecular Weight: 168.39
- MDL number: MFCD18633195
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-14 14:09:35
What is 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole?
Biological Activity
AN-2718 inhibits the growth of fungi by inhibiting protein synthesis through the OBORT mechanism.
in vitro
AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus , and from yeasts, C. albicans , with an IC 50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T. mentagrophytes .
Properties of 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
| Melting point: | 150-154 °C |
| Boiling point: | 273.2±50.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL |
| form | A crystalline solid |
| pka | 6.60±0.20(Predicted) |
| color | White to off-white |
Safety information for 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE ACICLOVIR AMLODIPINE SODIUM METHYL PARABEN Methylcobalamin (vitamin B12) SODIUM VALPROATE 5-Fluoro-2-iodo-3-methylaniline Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 3-Bromo-2-hydroxybenzeneacetic acid 5-Iodo-3-methyl-2-nitropyridine 1-(3-Chloro-2-hydroxyphenyl)-2-propanoneRelated products of tetrahydrofuran
![1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-5-carbonitrile](https://img.chemicalbook.in/CAS/20180703/GIF/905710-80-7.gif)
![6-chlorobenzo[c][1,2]oxaborol-1(3H)-ol](https://img.chemicalbook.in/CAS/20180703/GIF/174671-43-3.gif)
![6-(hydroxymethyl)benzo[c][1,2]oxaborol-1(3H)-ol](https://img.chemicalbook.in/CAS/20180703/GIF/947162-87-0.gif)
![1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborole-7-carboxylic acid](https://img.chemicalbook.in/CAS/20180808/GIF/1268335-28-9.gif)
You may like
-
![446292-08-6 (S)-2-{2-Oxo-3-[4-(3-oxo-morpholin-4-yl)-phenyl]-oxazolidin-5-ylmethyl}-isoindole-1,3-dione 99](https://img.chemicalbook.in//Content/image/CP5.jpg)
446292-08-6 (S)-2-{2-Oxo-3-[4-(3-oxo-morpholin-4-yl)-phenyl]-oxazolidin-5-ylmethyl}-isoindole-1,3-dione 99View Details
446292-08-6 -
494-19-9 >99View Details
494-19-9 -
Iminostilbene 256-96-2 98View Details
256-96-2 -
147403-52-9 > 99View Details
147403-52-9 -
5,6-Dimethoxy-2-(4-piperidinylmethyl)-1-indanone hydrochloride 120013-39-0 > 99.0View Details
120013-39-0 -
718635-93-9 3-(dimethylamino)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one >99%View Details
718635-93-9 -
120014-30-4 5,6-Dimethoxy-2-[(4-piperidyl) methyl]indan-1-one > 99.0View Details
120014-30-4 -
147403-65-4 > 99View Details
147403-65-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.