5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

Synonym(s):β-Adrenergic Receptor Kinase1 Inhibitor, GRK2 Inhibitor, Methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate;βARK1 Inhibitor - CAS 24269-96-3 - Calbiochem

CAS NO.：24269-96-3
Empirical Formula: C12H9NO6
Molecular Weight: 263.2
MDL number: MFCD00099039
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester Structural

What is 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester?

The Uses of 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.

What are the applications of Application

βARK1 Inhibitor is a selective inhibitor of GRK 2 (G protein-coupled receptor kinase 2)/βARK1 (β-Adrenergic Receptor Kinase 1).

Properties of 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

Melting point:	139-140 °C
Boiling point:	408.4±45.0 °C(Predicted)
Density	1.400±0.06 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Acetone (Slightly), Methanol (Slightly)
form	Solid
color	Pale Yellow to Yellow
Sensitive	Light Sensitive

Safety information for 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

Computed Descriptors for 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

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