4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
Synonym(s):6-Nitroveratryl alcohol
- CAS NO.:1016-58-6
- Empirical Formula: C9H11NO5
- Molecular Weight: 213.19
- MDL number: MFCD00014701
- EINECS: 213-806-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 15:28:16
What is 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL?
Chemical properties
white to light yellow crystal powde
The Uses of 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
4,5-Dimethoxy-2-nitrobenzyl alcohol (6-nitroveratryl alcohol) is suitable reagent used in the synthesis of 4,5-dimethoxy-2-nitrobenzyl methacrylate, a photolabile monomer and 2-(4-((4-(4,5-dimethoxy-2-nitrobenzyloxy)phenyl)cyclohexylidene)methyl)phenoxy)-N,N-dimethylethanamine, a caged cyclofen-OH ligand.
It may be used in the synthesis of the following:
- 1-[[(chlorocarbonyl)oxy]methyl]-4,5-dimethoxy-2-nitrobenzene
- bis(4,5-dimethoxy-2-nitrophenyl)ethylene glycol, a photolabile protecting group
- optically-sensitive monomer
- nitroveratryl (NV) protected α-hydroxyacetic acid (αG) (NV-αG-OH), required in the preparation of nitroveratryl (NV) protected cyanomethyl (CM) ester of α-hydroxyacetic acid (αG) (NV-αG-CM)
- 4,5-dimethoxy-2-nitrobenzyl p-nitro-phenylcarbonate
- 6-nitroveratryloxycarbonyl chloride (NVOCCl), a reagent used in the protection of amino function in amino sugars
The Uses of 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
4,5-Dimethoxy-2-nitrobenzyl alcohol, is used as Reagent for the protection of alcohols, etc., as ethers which can be cleaved by photolysis involving intramolecular rearrangement to derivatives of o-nitrosobenzaldehyde, which are readily cleaved by hydrolysis. It is also used as photochemical protecting groups in organic synthesis. It is also used as a pharmaceutical intermediate.
General Description
4,5-Dimethoxy-2-nitrobenzyl alcohol (6-Nitroveratryl Alcohol) is 2-nitrobenzyl alcohol derivative. It has been reported to be one of the oxidation products of veratryl (3,4-dimethoxybenzyl) alcohol by lignin peroxidase (isolated from Phanerochaete chrysosporium).
Properties of 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
Melting point: | 145-148 °C (lit.) |
Boiling point: | 383.9±37.0 °C(Predicted) |
Density | 1.307±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
form | powder to crystal |
pka | 13.59±0.10(Predicted) |
color | White to Yellow to Green |
Water Solubility | Soluble in water. |
Sensitive | Light Sensitive |
λmax | 400nm(CH3CN)(lit.) |
BRN | 1880093 |
CAS DataBase Reference | 1016-58-6(CAS DataBase Reference) |
Safety information for 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4,5-DIMETHOXY-2-NITROBENZYL ALCOHOL
Abamectin manufacturer
BASR Fine Chemicals Pvt. Ltd.
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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