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HomeProduct name list4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

Synonym(s):14-norlanosterol; 4,4-dimethylzymosterol; T-MAS; 110892;4,4-dimethylcholest-8(9),24-dien-3β-ol

4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol Structural

What is 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol?

The Uses of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

14-Norlanosterol, is a metabolite of Lanosterol (L174580). It is also a meiosis activating sterol (MAS), which is shown to have an important role in regulating meiosis and reproduction.

The Uses of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

14-demethyl-lanosterol has been used to reduce cancer cell viability and increase cancer cell sensitivity to erlotinib.

Definition

ChEBI: A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.

General Description

14-demethyl-lanosterol acts as an intermediate in cholesterol biosynthesis. It is used to stimulate oocytes for meiosis. 14-demethyl-lanosterol modulates cumulus expansion.

Properties of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

storage temp.  -70°C

Safety information for 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

Computed Descriptors for 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol

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