4,4-Diethoxy-N,N-dimethyl-1-butanamine
Synonym(s):N,N-Dimethyl-4-aminobutanal diethyl acetal;1-(N,N-Dimethylamino)-4,4-diethoxybutane;4,4-Diethoxy-N,N-dimethyl-1-butanamine;4,4-Diethoxy-N,N-dimethylbutanamine;4,4-Diethoxy-N,N-dimethylbutylamine
- CAS NO.：1116-77-4
- Empirical Formula: C10H23NO2
- Molecular Weight: 189.3
- MDL number: MFCD00671479
- EINECS: 601-109-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-27 17:36:02
What is 4,4-Diethoxy-N,N-dimethyl-1-butanamine?
Chemical properties
Light yellow liquid
The Uses of 4,4-Diethoxy-N,N-dimethyl-1-butanamine
4,4-Diethoxy-N,N-dimethyl-1-butanamine is used in organic synthesis and pharmaceutical intermediates, it is an intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan.
What are the applications of Application
4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs.
Preparation
4-Dimethylaminobutyraldehyde diethyl acetal synthesis: The reaction of 1-bromo-3-chloro propane and dimethylamine solution with PEG as a phase transfer catalyst, and obtained 3-dimethylamino-1-chloro propane. 3-dimethylamino-1-chloro propane reacted with magnesium and Grinard reagent was acquired. 4-Dimethylaminobutyraldehyde diethyl acetal is obtained by the reaction of Grinard reagent and triethyl orthoformate. The yield was 70.11%.
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 2401, 1994 DOI: 10.1016/0040-4039(94)85230-8
Properties of 4,4-Diethoxy-N,N-dimethyl-1-butanamine
| Boiling point: | 194-195C |
| Density | 0.844 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 158 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| pka | 9.71±0.28(Predicted) |
| color | Colourless to Pale Yellow |
| CAS DataBase Reference | 1116-77-4(CAS DataBase Reference) |
Safety information for 4,4-Diethoxy-N,N-dimethyl-1-butanamine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 4,4-Diethoxy-N,N-dimethyl-1-butanamine
Abamectin manufacturer
Vardhaman P Golechha
1Y
Phone:+91-9704422000
Whatsapp: +91 9704422000
product: 1116-77-4 4-DIMETHYLAMINO BUTYRALDEHYDE DIETHYL ACETAL 98%
Lakshmi Farmachem
1Y
Phone:+91-9550886476
Whatsapp: +91-9550886476
product: 4-Dimethylaminobutyraldehyde diethylacetal 98%
Synergene Active Ingredients Pvt. Ltd.
1Y
Phone:+9104023700774
product: 4-Dimethylaminobutyraldehyde diethylacetal 1116-77-4 98%
Ralington Pharma
1Y
Phone:+91-9687771722
Whatsapp: +91- 9687771722
product: 1116-77-4 4-Dimethylaminobutyraldehyde diethylacetal 98%
Aurazia Chem Laboratories Private Limited
1Y
Phone:+91-8754492844
Whatsapp: +91-8754492844
product: 1116-77-4 98%
Sibram Pharmaceutical
1Y
Phone:+91-8655777550
Whatsapp: +91-8655777550
product: 4-Dimethylaminobutyraldehyde diethylacetal 99%
New Products
3-Pyridineacrylic acid 3-Bromo-4-fluorophenol N-Boc-Ethylenediamine cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 4-Aminotetrahydropyran hydrochloride 4,5-Dibromopyridazin-3-one N-Benzyl-3-hydroxypiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,4-Dichloro-5-Methylpyridine 2-Amino-6-Chloro-3-Nitropyridine 2-Chloro-4-Nitropyridine-N-Oxide 3-Amino-5-Chloropyridine 2-Fluoroisonicotinic acid 2-Hydroxy-5-Methylpyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-AminophenaethylalcholRelated products of tetrahydrofuran
You may like
-
1116-77-4 4-DIMETHYLAMINO BUTYRALDEHYDE DIETHYL ACETAL 98%View Details
1116-77-4 -
1116-77-4 98%View Details
1116-77-4 -
4-Dimethylaminobutyraldehyde diethylacetal 98%View Details
-
4-Dimethylaminobutyraldehyde diethylacetal 1116-77-4 98%View Details
1116-77-4 -
1116-77-4 4-Dimethylaminobutyraldehyde diethylacetal 98%View Details
1116-77-4 -
1116-77-4 98%View Details
1116-77-4 -
4-Dimethylaminobutyraldehyde diethylacetal 99%View Details
1116-77-4 -
(R)-2-methylpyrolidine-2-carboxylic acid (DeMepro) >98%View Details
63399-77-9
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.