4-PHENOXYBENZYLAMINE

CAS NO.：107622-80-0
Empirical Formula: C13H13NO
Molecular Weight: 199.25
MDL number: MFCD01310836
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 16:21:11

What is 4-PHENOXYBENZYLAMINE?

Biological Activity

4-Phenoxybenzylamine inhibits the function of NS3 protein by stabilizing the inactive conformation, and inhibits FL NS3/4a with an IC50 value of approximately 500 μM.

in vitro

A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents.

Properties of 4-PHENOXYBENZYLAMINE

Boiling point:	138°C 5mm
Density	1,12 g/cm³
refractive index	1.59
Flash point:	150℃
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in DMSO
form	clear liquid
pka	9.13±0.10(Predicted)
color	Colorless to Light orange to Yellow
CAS DataBase Reference	107622-80-0(CAS DataBase Reference)

Safety information for 4-PHENOXYBENZYLAMINE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.