4-NITROPHENYL ISOTHIOCYANATE
- CAS NO.:2131-61-5
- Empirical Formula: C7H4N2O2S
- Molecular Weight: 180.18
- MDL number: MFCD00007307
- EINECS: 218-359-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-26 14:19:27
What is 4-NITROPHENYL ISOTHIOCYANATE?
Chemical properties
yellow crystalline powder
The Uses of 4-NITROPHENYL ISOTHIOCYANATE
4-Nitrophenyl isothiocyanate is used as specializing in synthesizing of organic fine chemicals and pharmaceutical intermediates for use in development and production
The Uses of 4-NITROPHENYL ISOTHIOCYANATE
4-Nitrophenyl isothiocyanate has been used in the synthesis of:
- 5,6-dimethyl-2-[(4-nitrophenyl)amino]thieno[2,3-d]pyrimidin-4(3H)-one
- 4,5-dimethyl-2-substituted carbamothioylaminothiophene-3-carboxamides
- acyclic triazene or zwitterionic dihydropyrimidinium imidothiolate derivatives
Production Methods
4-nitrophenyl isothiocyanat can be produced from para-Nitroaniline with Thiophosgene, or from para-Nitrothiocarbanilide by heating with diluted sulfuric acid.
Synthesis Reference(s)
The Journal of Organic Chemistry, 37, p. 1360, 1972 DOI: 10.1021/jo00974a016
General Description
The solid-state reactivity of hydrazine hydrochloride with 4-nitrophenyl isothiocyanate was studied.
Properties of 4-NITROPHENYL ISOTHIOCYANATE
Melting point: | 110-112 °C(lit.) |
Boiling point: | 137-138 °C11 mm Hg(lit.) |
Density | 1.4360 (rough estimate) |
refractive index | 1.6000 (estimate) |
Flash point: | 137-138°C/11mm |
storage temp. | Store at <= 20°C. |
solubility | Very slightly soluble in alcohol and oils. |
form | powder to crystal |
color | Light orange to Yellow to Green |
Odor | Pungent-sweet herbaceous-spicy odor with resemblance to Bitter-almond and remote similarity to Heliotropine. |
Water Solubility | It hydrolyzes with water. Soluble in toluene. |
Sensitive | Moisture Sensitive |
BRN | 640027 |
CAS DataBase Reference | 2131-61-5(CAS DataBase Reference) |
EPA Substance Registry System | Benzene, 1-isothiocyanato-4-nitro- (2131-61-5) |
Safety information for 4-NITROPHENYL ISOTHIOCYANATE
Signal word | Danger |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-NITROPHENYL ISOTHIOCYANATE
InChIKey | NXHSSIGRWJENBH-UHFFFAOYSA-N |
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
SEC-BUTYL ISOTHIOCYANATE
Ethoxycarbonyl Isothiocyanate
ETHYL ISOTHIOCYANATOACETATE
2,3-DICHLOROPHENYL ISOTHIOCYANATE
CYCLOPENTYL ISOTHIOCYANATE
ISOBUTYL ISOTHIOCYANATE
3-BROMOPHENYL ISOTHIOCYANATE
CYCLOPROPYL ISOTHIOCYANATE
You may like
-
2131-61-5 3-Nitrophenyl isothiocyanate 99%View Details
2131-61-5 -
2131-61-5 99%View Details
2131-61-5 -
4-Nitrophenyl isothiocyanate CAS 2131-61-5View Details
2131-61-5 -
4-Nitrophenyl Isothiocyanate CAS 2131-61-5View Details
2131-61-5 -
4-Nitrophenyl isothiocyanate CAS 2131-61-5View Details
2131-61-5 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.