4-Nitrophenethyl bromide

Synonym(s):1-(2-Bromoethyl)-4-nitrobenzene;2-(4-Nitrophenyl)ethyl bromide

CAS NO.：5339-26-4
Empirical Formula: C8H8BrNO2
Molecular Weight: 230.06
MDL number: MFCD00007386
EINECS: 226-271-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-25 23:13:37

What is 4-Nitrophenethyl bromide?

Chemical properties

yellowish adhering crystals or crystalline powder

The Uses of 4-Nitrophenethyl bromide

4-nitrophenethyl bromide is used a s a GST T1-1 substrate for identifying many kinetic parameters (Km, Kcat) for hGST T1-1 variants.

What are the applications of Application

4-Nitrophenethyl bromide is a GST T1-1 substrate

General Description

4-nitrophenethyl bromide is an electrophile which accepts a lone pair of electrons from one of the nitrogen atoms in the polyazamacrocycle.

Biochem/physiol Actions

4-Nitrophenethyl bromide is used as a marker in for the θ-class of glutathione S-transferases (GSTs). It activates the human θ-class glutathione transferase T1-1 enzyme.

Properties of 4-Nitrophenethyl bromide

Melting point:	67-69 °C (lit.)
Boiling point:	116°C/0.2mm
Density	1.6270 (rough estimate)
refractive index	1.6120 (estimate)
Flash point:	116°C/0.2mm
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform(Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form	Adhering Crystals or Crystalline Powder
color	Yellow
Water Solubility	Soluble in water (partly) and methanol.
BRN	1909321
CAS DataBase Reference	5339-26-4(CAS DataBase Reference)
NIST Chemistry Reference	1-Bromo-2-(4-nitrophenyl)ethane(5339-26-4)

Safety information for 4-Nitrophenethyl bromide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.