4-METHYLPYRAZOLE HYDROCHLORIDE
Synonym(s):Fomepizole
- CAS NO.：56010-88-9
- Empirical Formula: C4H7ClN2
- Molecular Weight: 118.56
- MDL number: MFCD00012707
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is 4-METHYLPYRAZOLE HYDROCHLORIDE?
The Uses of 4-METHYLPYRAZOLE HYDROCHLORIDE
4-Methylpyrazole hydrochloride has been used:
- as a cytochrome P450 2E1 inhibitor
- as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells
- to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells
What are the applications of Application
4-Methylpyrazole hydrochloride is a product for proteomics research
Biochem/physiol Actions
4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.
Properties of 4-METHYLPYRAZOLE HYDROCHLORIDE
| Melting point: | 157-159 °C |
| storage temp. | 2-8°C |
Safety information for 4-METHYLPYRAZOLE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-METHYLPYRAZOLE HYDROCHLORIDE
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![N'1-[(5-CHLORO-1,3-DIMETHYL-1H-PYRAZOL-4-YL)METHYLIDENE]-4-METHYLBENZENE-1-CARBOHYDRAZIDE](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB5343186.gif)
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