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HomeProduct name list4-METHYLPYRAZOLE HYDROCHLORIDE

4-METHYLPYRAZOLE HYDROCHLORIDE

Synonym(s):Fomepizole

4-METHYLPYRAZOLE HYDROCHLORIDE Structural

What is 4-METHYLPYRAZOLE HYDROCHLORIDE?

The Uses of 4-METHYLPYRAZOLE HYDROCHLORIDE

4-Methylpyrazole hydrochloride has been used:

  • as a cytochrome P450 2E1 inhibitor
  • as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells
  • to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells

What are the applications of Application

4-Methylpyrazole hydrochloride is a product for proteomics research

Biochem/physiol Actions

4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.

Properties of 4-METHYLPYRAZOLE HYDROCHLORIDE

Melting point: 157-159 °C
storage temp.  2-8°C

Safety information for 4-METHYLPYRAZOLE HYDROCHLORIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-METHYLPYRAZOLE HYDROCHLORIDE

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