4-Methylenepiperidine HCl
- CAS NO.：144230-50-2
- Empirical Formula: C6H12ClN
- Molecular Weight: 133.62
- MDL number: MFCD17977038
- EINECS: 820-104-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-14 13:42:19
What is 4-Methylenepiperidine HCl?
The Uses of 4-Methylenepiperidine HCl
4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.
Synthesis
4-Methylenepiperidine hydrochloride can be synthesized by reacting ethylene with an alkoxide, followed by adding a metal halide such as organolithium reagents to form the desired product. The yield rate of this reaction is high and it is easy to perform on a large scale.
Properties of 4-Methylenepiperidine HCl
| Melting point: | 148-151°C (Subl.) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Stability: | Light Sensitive |
Safety information for 4-Methylenepiperidine HCl
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Methylenepiperidine HCl
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