4-METHOXY-3-NITROACETOPHENONE

CAS NO.：6277-38-9
Empirical Formula: C9H9NO4
Molecular Weight: 195.17
MDL number: MFCD00017023
EINECS: 228-476-7
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 4-METHOXY-3-NITROACETOPHENONE?

The Uses of 4-METHOXY-3-NITROACETOPHENONE

4′-Methoxy-3′-nitroacetophenone may be used to synthesize dimethylamino compound, via W₂ Raney nickel catalyzed reductive methylation.

Preparation

Preparation by reaction of acetyl chloride with 2-nitroanisole in the presence of aluminium chloride,
? in nitrobenzene at 0° ;
? in carbon disulfide.

General Description

4′-Methoxy-3′-nitroacetophenone can be synthesized from p-methoxyacetophenone via nitration.

Properties of 4-METHOXY-3-NITROACETOPHENONE

Melting point:	97-100 °C(lit.)
Boiling point:	315.1±22.0 °C(Predicted)
Density	1.244±0.06 g/cm3(Predicted)
form	powder to crystal
color	White to Yellow to Green
BRN	646069
CAS DataBase Reference	6277-38-9(CAS DataBase Reference)

Safety information for 4-METHOXY-3-NITROACETOPHENONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.