4-Hydroxy-2-methylquinoline
Synonym(s):2-Methyl-4-quinolinol
- CAS NO.：607-67-0
- Empirical Formula: C10H9NO
- Molecular Weight: 159.18
- MDL number: MFCD00006758
- EINECS: 210-140-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-25 18:01:12
What is 4-Hydroxy-2-methylquinoline?
Chemical properties
BEIGE POWDER
The Uses of 4-Hydroxy-2-methylquinoline
4-Hydroxy-2-methylquinoline is act as an intermediate in the synthesis of dequalinium chloride and as pharmaceutical intermediate.
The Uses of 4-Hydroxy-2-methylquinoline
4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:
- Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
- Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
- Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
- Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.
Definition
ChEBI: 2-Methyl-4-quinolinol is a member of quinolines.
Properties of 4-Hydroxy-2-methylquinoline
| Melting point: | 234-236 °C(lit.) |
| Boiling point: | 284.68°C (rough estimate) |
| Density | 1.1202 (rough estimate) |
| refractive index | 1.6070 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 4.44±0.40(Predicted) |
| color | White to Light yellow |
| Water Solubility | Slightly soluble in water. |
| λmax | 317nm(CHCl3)(lit.) |
| BRN | 118320 |
| CAS DataBase Reference | 607-67-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Quinolinol, 2-methyl-(607-67-0) |
Safety information for 4-Hydroxy-2-methylquinoline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Hydroxy-2-methylquinoline
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