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HomeProduct name list4-Hydroxy-2-methylquinoline

4-Hydroxy-2-methylquinoline

Synonym(s):2-Methyl-4-quinolinol

  • CAS NO.:607-67-0
  • Empirical Formula: C10H9NO
  • Molecular Weight: 159.18
  • MDL number: MFCD00006758
  • EINECS: 210-140-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-25 18:01:12
4-Hydroxy-2-methylquinoline Structural

What is 4-Hydroxy-2-methylquinoline?

Chemical properties

BEIGE POWDER

The Uses of 4-Hydroxy-2-methylquinoline

4-Hydroxy-2-methylquinoline is act as an intermediate in the synthesis of dequalinium chloride and as pharmaceutical intermediate.

The Uses of 4-Hydroxy-2-methylquinoline

4-Hydroxy-2-methylquinoline can be used as an intermediate in the synthesis of a wide range of medicinally important compounds such as:

  • Synthesis of 2-(quinolin-4-yloxy)acetamides as potent antitubercular agents.
  • Synthesis of 2-arylethenylquinoline derivatives for the treatment of Alzheimer′s disease.
  • Synthesis of 1,10-diethoxy-1H-pyrano[4,3-b]quinolones as antibacterial agents.
  • Synthesis of phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phophodiesterase 10A (PDE10A) inhibitors.

Definition

ChEBI: 2-Methyl-4-quinolinol is a member of quinolines.

Properties of 4-Hydroxy-2-methylquinoline

Melting point: 234-236 °C(lit.)
Boiling point: 284.68°C (rough estimate)
Density  1.1202 (rough estimate)
refractive index  1.6070 (estimate)
storage temp.  Sealed in dry,Room Temperature
form  powder to crystal
pka 4.44±0.40(Predicted)
color  White to Light yellow
Water Solubility  Slightly soluble in water.
λmax 317nm(CHCl3)(lit.)
BRN  118320
CAS DataBase Reference 607-67-0(CAS DataBase Reference)
NIST Chemistry Reference 4-Quinolinol, 2-methyl-(607-67-0)

Safety information for 4-Hydroxy-2-methylquinoline

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-Hydroxy-2-methylquinoline

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