4-HYDROXY-1-METHYL-2-QUINOLONE

CAS NO.：1677-46-9
Empirical Formula: C10H9NO2
Molecular Weight: 175.18
MDL number: MFCD00024052
EINECS: 216-830-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is 4-HYDROXY-1-METHYL-2-QUINOLONE?

The Uses of 4-HYDROXY-1-METHYL-2-QUINOLONE

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones. It was used in the synthesis of :

3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone
3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one
3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one
3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one

Properties of 4-HYDROXY-1-METHYL-2-QUINOLONE

Melting point:	269-271 °C (lit.)
Boiling point:	306.47°C (rough estimate)
Density	1.326
refractive index	1.5060 (estimate)
pka	4.50±1.00(Predicted)
form	powder to crystal
color	Light yellow to Brown to Dark green
CAS DataBase Reference	1677-46-9(CAS DataBase Reference)
EPA Substance Registry System	2(1H)-Quinolinone, 4-hydroxy-1-methyl- (1677-46-9)

Safety information for 4-HYDROXY-1-METHYL-2-QUINOLONE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.