4-Fluoro-3-nitrobenzotrifluoride

Synonym(s):3-Nitro-α,α,α,4-tetrafluorotoluene;4,α,α,α-Tetrafluoro-3-nitrotoluene;FNBT

CAS NO.：367-86-2
Empirical Formula: C7H3F4NO2
Molecular Weight: 209.1
MDL number: MFCD00007059
EINECS: 206-702-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-13 17:19:14

4-Fluoro-3-nitrobenzotrifluoride Structural

What is 4-Fluoro-3-nitrobenzotrifluoride?

Chemical properties

clear yellow liquid

The Uses of 4-Fluoro-3-nitrobenzotrifluoride

4-Fluoro-3-nitrobenzotrifluoride is used in the pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines. It may be used as derivatization reagent for the HPLC determination of polyamines. It was also used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids. ? [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids3 ? 1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one

The Uses of 4-Fluoro-3-nitrobenzotrifluoride

4-Fluoro-3-nitrobenzotrifluoride was used in pre-column derivatization technique for HPLC with UV/VIS spectrophotometric detection of polyamines.
It was also used in the synthesis of:

2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids
[3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids
1-(3-chlorophenyl)-5-trifluoromethyl-3-hydrobenzimidazol-2-one

Properties of 4-Fluoro-3-nitrobenzotrifluoride

Boiling point:	92 °C15 mm Hg(lit.)
Density	1.494 g/mL at 25 °C(lit.)
refractive index	n20/D 1.462(lit.)
Flash point:	92 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Sparingly)
form	Liquid
color	deep greenish-yellow
Water Solubility	Insoluble in water.
BRN	1880508
CAS DataBase Reference	367-86-2(CAS DataBase Reference)
NIST Chemistry Reference	4-Fluoro-3-nitrobenzotrifluoride(367-86-2)
EPA Substance Registry System	Benzene, 1-fluoro-2-nitro-4-(trifluoromethyl)- (367-86-2)

Safety information for 4-Fluoro-3-nitrobenzotrifluoride

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.