4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonym(s):(4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride;4-Epianhydrotetracycline hydrochloride
- CAS NO.:4465-65-0
- Empirical Formula: C22H23ClN2O7
- Molecular Weight: 462.88
- MDL number: MFCD00151455
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE?
Chemical properties
orange powder
The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.
The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.
What are the applications of Application
4-Epianhydrotetracycline Hydrochloride is the epi- derivative of Tetracycline
Properties of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Melting point: | 220 °C |
storage temp. | -20°C Freezer |
solubility | DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml |
form | Powder |
color | Orange |
BRN | 3840711 |
EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0) |
Safety information for 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Computed Descriptors for 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1,1’-CARBONYLDIIMIDAZOLE DIETHYL AMINOMALONATE HYDROCHLORIDE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
1'-HYDROXY-2'-ACETONAPHTHONE
4-EPIANHYDROCHLORTETRACYCLINE HYDROCHLORIDE, CAN BE USED AS SECONDARY STANDARD
1,3-DIMETHYLNAPHTHALENE
4-EPIANHYDROTETRACYCLINE
5-Methylnaphthalene-1-ol
1,2,3-TRIMETHYLNAPHTHALENE
C-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-METHYLAMINE
1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBALDEHYDE
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