4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Synonym(s):(4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride;4-Epianhydrotetracycline hydrochloride

CAS NO.：4465-65-0
Empirical Formula: C22H23ClN2O7
Molecular Weight: 462.88
MDL number: MFCD00151455
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-23 13:36:13

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Structural

What is 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE?

Chemical properties

orange powder

The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

The Uses of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

What are the applications of Application

4-Epianhydrotetracycline Hydrochloride is the epi- derivative of Tetracycline

Properties of 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Melting point:	220 °C
storage temp.	-20°C Freezer
solubility	DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form	Powder
color	Orange
BRN	3840711
EPA Substance Registry System	2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)