4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE
Synonym(s):4-Cyclohexylmethoxy-2,6-diamino-5-nitrosopyrimidine
- Empirical Formula: C11H17N5O2
- Molecular Weight: 251.28
- MDL number: MFCD05664735
- Update Date: 2023-04-23 13:52:06
What is 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE?
The Uses of 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE
NU6027 is a potent cyclin-dependent kinase (CDK) and Rad3-related kinase (ATR) inhibitor. NU6027 has been shown to inhibit tumor cell growth. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and poly(ADP-ribose) polymerase (PARP) inhibitors
Properties of 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE
| Melting point: | 252.5-253.7 °C(lit.) |
| storage temp. | 2-8°C |
| solubility | DMSO: 15 mg/mL |
| color | lavender |
Safety information for 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE
Computed Descriptors for 4-CYCLOHEXYLMETHOXY-2,6-DIAMINO-5-NITROSOPYRIMIDINE
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